Review Article

Purinergic Receptors in Ocular Inflammation

Figure 2

Regulation of retinal inflammation by adenosine receptor. Pathways proposed to be involved in anti-inflammatory effect of adenosine receptor in the retinal microglial cells during pathologies such as diabetes or traumatic optic neuropathy. adenosine receptor activation reduces TNF-α release by repressing the inflammatory cascade C-Raf/ERK in activated retinal microglia.
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