Induction of IL-12 Production in Human Peripheral Monocytes by <i>Trypanosoma cruzi</i> Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-<b><i>γ</i></b> and CD40-CD40L Interactions

<table>tGPI-mucins from<i> T. cruzi</i> induce IL-12 production by human monocytes. Results come from 3 distinct experiments. Groups were compared by a nonparametrical test (Mann-Whitney Rank Sum Test) with GraphPad InStat software (version 5.0; GraphPad). Results were expressed as medians and interquartile ranges. <svg height="11.175" id="M3" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 10.9375 11.175" width="10.9375" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" id="x1D443"></path></g>
</svg> values were considered significant if &lt;0.05.</table>

Mediators of Inflammation

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Figure 3

Figure 3: Induction of IL-12 Production in Human Peripheral Monocytes by <i>Trypanosoma cruzi</i> Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-<b><i>γ</i></b> and CD40-CD40L Interactions 

Figure 3 | Induction of IL-12 Production in Human Peripheral Monocytes by Trypanosoma cruzi Is Mediated by Glycosylphosphatidylinositol-Anchored Mucin-Like Glycoproteins and Potentiated by IFN-γ and CD40-CD40L Interactions 