Can the TLR-4-Mediated Signaling Pathway Be “A Key Inflammatory Promoter for Sporadic TAA”?

Table 3

Frequency of +896ATLR4/DACE/−1562TMMP-9/−735TMMP-2 “high responder” (proinflammatory) genotype between patients and controls (2×2 comparisons between the different groups with odd ratio (OR) and 95% confidence interval).

Subjects	+896ATLR4/DACE/−1562TMMP-9/−735TMMP-2 “high responder”	Other genotypes	𝑃; (2×2 Table)	OR (95% CI)
Patients (𝑁=161)	46	115	𝐏=𝟎.𝟎𝟎𝟎𝟎𝟎𝟗	4.7 (2.7–9.8) 𝐏<𝟎.𝟎𝟎𝟎𝟏
Controls (𝑁=128)	10	118