Functional Roles of p38 Mitogen-Activated Protein Kinase in Macrophage-Mediated Inflammatory Responses

Table 4

p38 inhibitors under human clinical trials.

Compound	Clinical trials	Reference
PH797804	Chronic obstructive pulmonary disease (COPD)	[132]
Losmapimod (GW856553)	COPD; atherosclerosis	[133, 134]
Adalimumab	Antipsoriatic	[135]
Pamapimod	Rheumatoid arthritis	[136]
VX-745	Werner syndrome	[137]
BMS-582949	Rheumatoid arthritis	[138]
SB-681323	Percutaneous coronary intervention (PCI); neuropathic pain	[139, 140]