Obesity and Low-Grade Inflammation Increase Plasma Follistatin-Like 3 in Humans
Table 2
Correlation between plasma follistatin-like 3 and demographic and biochemical characteristics.
Total ()
Control ()
IGT ()
T2DM ()
Spearman’s
Spearman’s
Spearman’s
Spearman’s
Age (years)
0.197**
0.202
0.037
0.331**
Weight (kg)
0.318***
0.278*
0.364**
0.309*
Height (m)
−0.178*
−0.135
−0.162
−0.185
Hip (cm)
0.468***
0.428***
0.543***
0.453***
Waist (cm)
0.457***
0.372***
0.479***
0.557***
BMI (kg/m2)
0.477***
0.420***
0.547***
0.447***
Systolic BP (mmHg)
0.020
0.008
0.005
0.046
Diastolic BP (mmHg)
0.086
0.160
0.033
0.067
VO2max (mL/min/kg)
−0.347***
−0425***
−0.146
−0.436***
Whole body fat (kg)
0.585***
0.560***
0.598***
0.624***
Trunk fat mass (kg)
0.558***
0.521***
0.585***
0.595***
Whole body fat-free mass (kg)
−0.055
−0.058
0.073
−0.113
Insulin (fasting) (pM)
0.448***
0.378***
0.415**
0.554***
Glucose (fasting) (mM)
0.007
0.054
0.020
−0.071
c-peptide (nM)
0.453***
0.409***
0.380**
0.598***
HOMA B
0.372***
0.398***
0.371**
0.455***
HOMA S
−0.433***
−0.368***
−0.376**
−0.566***
TNF- (pg/mL)
0.362***
0.128
0.250
0.593***
IL-6 (pg/mL)
0.497***
0.371***
0.363**
0.695***
Leptin (pg/mL)
0.598***
0.614***
0.545***
0.629***
Adiponectin (ug/mL)
0.044
−0.018
−0.040
0.176
Spearman’s correlation coefficient is given for each variable in all subjects and in the different glycaemia groups. Spearman’s correlation coefficient is given for each variable. The whole study group included 200 subjects except for hip (), waist (), BMI (), (), whole body fat (), whole body fat-free mass (). The control group consisted of 78 subjects, the IGT of 58 subjects except for (), whole body fat (), whole body fat-free mass (), and the T2DM of 64 except for hip (), waist (), whole body fat (), and whole body fat-free mass (). HOMA S: homeostasis model assessment of insulin sensitivity. HOMA B: homeostasis model assessment of beta cell function. BMI: body mass index. indicates a significant correlation between plasma fstl3 and the given variable. , , and .
