Protective Effect of Laminaria japonica with Probiotics on Murine Colitis

Figure 3

(a) Effects of LJE or DUO on clinical score in DSS-induced colitis. (b) Effects of LJE or DUO on gross macroscopic finding of colon in DSS-induced colitis. (c) Effects of LJE or DUO on cecum edema in DSS-induced colitis. (d) Effects of LJE or DUO on cecum diameter in DSS-induced colitis. Data are expressed as mean ± S.E.M (𝑛=7). Nor: normal mice without any treatment, Con: mice provided with only 5% DSS treatment, LJE: the water extract of Laminaria japonica, DUO: Duolac7S, LJE + DUO: cotreatment of LJE and DUO, 100: the dosage of LJE 100 mg/kg, and 300: the dosage of LJE 300 mg/kg; ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 versus control group analyzed by one-way ANOVA with Dunnett’s post hoc test.

(a)

(b)

(c)

(d)