Mediators of Inflammation / 2014 / Article / Tab 5

Research Article

Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

Table 5

Inflammatory parameters at baseline (J0) and after 12 weeks (M3) of placebo or statin treatment.

J0M3Change M3 − J0 Difference in change (95% CI)

hs-CRP (mg/L)
 Placebo ()2.5 (−3.8; 8.8)
 Statin ()
Urinary LTE4 (pg/mg creatinine)
 Placebo ()14.1 (−10.4; 38.6)
 Statin ()
Urinary 11-DHTXB2 (pg/mg creatinine)
 Placebo ()41.0 (−156.9; 238.9)
 Statin ()

Data are mean ± SD. hs-CRP, high-sensitivity C-reactive protein; LTE4, leukotriene E4; 11-DHTXB2, 11-dehydro- thromboxane B2; TXB2, thromboxane B2.