Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial

Table 5

Inflammatory parameters at baseline (J0) and after 12 weeks (M3) of placebo or statin treatment.

	J0	M3	Change M3 − J0	Difference in change (95% CI)
hs-CRP (mg/L)
Placebo ()				2.5 (−3.8; 8.8)
Statin ()
Urinary LTE4 (pg/mg creatinine)
Placebo ()				14.1 (−10.4; 38.6)
Statin ()
Urinary 11-DHTXB2 (pg/mg creatinine)
Placebo ()				41.0 (−156.9; 238.9)
Statin ()

Data are mean ± SD. hs-CRP, high-sensitivity C-reactive protein; LTE4, leukotriene E4; 11-DHTXB2, 11-dehydro- thromboxane B2; TXB2, thromboxane B2.