Research Article
Vitamin C Mitigates Oxidative Stress and Tumor Necrosis Factor-Alpha in Severe Community-Acquired Pneumonia and LPS-Induced Macrophages
Table 1
Descriptive statistical analysis of the study groups.
| | | Control | Nonsevere pneumonia | Severe pneumonia |
| | Number | 15 | 15 | 15 | | Sex, m/f | 8/7 | 9/6 | 11/4 | | Age, years | 64.28 (4.12) | 61.26 (3.19) | 65.21 (4.56) | |
PaO2 mmHg | — | 99.8 (12.3) | 41.2 (8.2) | | PaCO2 mmHg | — | 35.2 (4.8) | 43.2 (3.9) | | PaO2/FiO2 mmHg | — | 321 (35) | 196 (42) | | Klebsiella pneumoniae | — | 2 | 2 | | Escherichia coli | — | 3 | 2 | | Cinetobacter | — | 3 | 4 | | Endotoxin (pg/mL) | — | 28.13 (4.14) | 39.34 (5.12) |
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Data are shown as means (SD).
M: male; F: female; FiO2: fraction of inspired oxygen; ST: patient temperature during sampling.
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