Research Article

Effects of Cholinergic Stimulation with Pyridostigmine Bromide on Chronic Chagasic Cardiomyopathic Mice

Figure 5

Serum cytokines after treatment with pyridostigmine bromide. Serum levels (in pg/mL) expressed as mean ± S.E.M. of tumor necrosis factor-α (TNF-α: Panel (a)), interleukin-5 (IL-5: Panel (b)) measured by the cytometric bead array technique, interferon-γ (IFN-γ: Panel (c)), and interleukin-10 (IL-10: Panel (d)) measured by ELISA at the 6th month of observation and after one month of treatment (from the 5th to 6th month of infection) in noninoculated control (Con) or T. cruzi-inoculated (Chg) C57BL/6j mice treated or not (NT) with pyridostigmine bromide (Pyrido). ( versus Con-NT; versus Chg-Pyrido; and versus Con-Pyrido).
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(a)
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(b)
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(c)
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(d)