Consequences of the Lack of CD73 and Prostatic Acid Phosphatase in the Lymphoid Organs

Figure 3

Purine-converting activities in CD73 and PAP deficient mice. The activities of ecto-5′-nucleotidase/AMPase (a), ATPase (b), ADPase (c), adenylate kinase (d), and adenosine deaminase (e) were determined by TLC in lymph node lymphocytes from wild type mice (), CD73 single (), PAP single (), and CD73/PAP double knockouts (). Enzymatic activities were expressed as nanomoles of ³H-substrate metabolized per hour by 10⁶ cells. , .

(a)

(b)

(c)

(d)

(e)