Puerarin Alleviates Neuropathic Pain by Inhibiting Neuroinflammation in Spinal Cord
Figure 3
The effects of puerarin on CCI-induced microglia and astroglia activation in ipsilateral spinal dorsal horn of rats. (a) and (b) Representative images of ipsilateral spinal dorsal microglia (a) and astroglia (b) activation in control rats, CCI rats, CCI rats receiving vehicle, 20 and 100 nM puerarin on the 11th day after CCI surgery. Scale bar: 100 μm. (c) Quantification of microglia activation in the spinal cord on the 11th day after CCI surgery. CCI: chronic constriction injury. Data are presented as mean ± SEM. , CCI model versus control; , puerarin versus CCI model (one-way ANOVA with post hoc LSD -test). Each group consisted of 6–10 rats.
