Auricular Electroacupuncture Reduced Inflammation-Related Epilepsy Accompanied by Altered TRPA1, pPKCα, pPKCε, and pERk1/2 Signaling Pathways in Kainic Acid-Treated Rats
Establishment of epilepsy rats was monitored by electroencephalographic (EEG) signals. Baseline EEG activity in the sensorimotor cortex was characterized by 6–8 Hz activity in rats when awake (a). KA-induced temporal lobe seizures, including wet-dog shakes (WDS) with intermittent polyspike-like activity (b), facial myoclonia with continuous sharp waves (c), and paw tremor (PT) with continuous spike activity (d). All signals were counted and displayed as bar chart (e). Each type of seizure had its own characteristic EEG activity. Lt Cx = EEG recording of the left sensorimotor cortex; Rt Cx = EEG recording of the right sensorimotor cortex; EMG = EMG recording of the neck muscle.