Long-Term Home Noninvasive Mechanical Ventilation Increases Systemic Inflammatory Response in Chronic Obstructive Pulmonary Disease: A Prospective Observational Study
Table 5
Clinical results.
Long-term oxygen therapy
Noninvasive ventilation
P value
Overall population
Before matching
Follow-up (months)
24.0 (21.0–25.5)
24.0 (24.0–24.0)
0.190
Prior hospitalizations
2.0 (1.0–3.0)
2.5 (1.0–4.0)
0.498
Subsequent hospitalizations
2.0 (1.0–4.0)
1.0 (0–2.0)
0.005
All hospitalizations
4.0 (2.0–7.0)
4.0 (2.0–6.8)
0.536
Death
10 (22.2%)
13 (27.1%)
0.587
After matching
Follow-up (months)
24.0 (22.5–25.0)
24.0 (22.5–24.0)
0.198
Prior hospitalizations
3.0 (2.0–3.0)
2.0 (1.0–3.3)
0.564
Subsequent hospitalizations
2.5 (1.0–4.0)
1.0 (0–1.3)
<0.001
All hospitalizations
5.0 (3.0–7.0)
3.0 (1.8–5.0)
0.021
Death
7 (23.3%)
9 (30.0%)
0.976
Excluding cross-overs
Before matching
Follow-up (months)
24.0 (16.5–25.0)
24.0 (24.0-24.0)
0.325
Prior hospitalizations
2.0 (1.0–3.0)
2.5 (1.0–4.0)
0.282
Subsequent hospitalizations
2.0 (1.0–3.0)
1.0 (0–2.0)
0.024
All hospitalizations
4.0 (2.0–5.3)
4.0 (2.0–6.8)
0.885
Death
9 (23.7%)
13 (27.1%)
0.720
After matching
Follow-up (months)
24.5 (22.5–25.0)
24.0 (22.5–24.0)
0.168
Prior hospitalizations
2.0 (2.0–3.0)
2.0 (1.0–3.3)
0.980
Subsequent hospitalizations
2.0 (1.0–3.0)
1.0 (0–1.3)
0.001
All hospitalizations
4.5 (3.0–6.0)
3.0 (1.8–5.0)
0.082
Death
6 (23.1%)
9 (30.0%)
0.560
reported as median (1st–3rd quartile) or (%) and compared with Mann-Whitney -test, chi-squared test, or Fisher’s exact test.
