Could Biomarkers of Bone, Cartilage or Synovium Turnover Be Used for Relapse Prediction in Rheumatoid Arthritis Patients?

Table 1

Synovium biomarkers and their interests in RA management.

Synovial biomarker	Expressed in RA	Treatment response	Joint destruction	Effects on monitoring in clinical response and progression
MMP-3	[23, 24]	[32–35]	[25, 27, 29–31]	[36]
Glc-Gal-PYD	[28, 39, 40]	No data available	[28, 39, 41]	No data available
IIINys	[44]	No data available	No data available	No data available

MMP-3: matrix metalloproteinase-3; Glc-Gal-PYD: glucosyl-galactosyl pyridinoline; IIINys: nitrated type III collagen.