Review Article

Could Biomarkers of Bone, Cartilage or Synovium Turnover Be Used for Relapse Prediction in Rheumatoid Arthritis Patients?

Table 2

More studied cartilage biomarkers and their interests in RA management.

Cartilage biomarkerExpressed in RATreatment responseJoint destruction

CTX-II [28, 47][41][28, 41, 47]
COMP [49][37][49]
PIIANP[50]No data availableNo data available

CTX-II: collagen type II C-telopeptide; COMP: cartilage oligomeric matrix protein; PIIANP: propeptide of type IIA procollagen.