Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

Figure 2

Effects of sitagliptin treatment on renal lesions in the kidney induced by diabetes, such as glomerular atrophy (a) and interstitial fibrosis/tubular atrophy (IFTA) (b) in ZDF (+/+) and ZDF (fa/fa) nontreated or treated with sitagliptin. (a1) and (b1) are representative images of renal histology (PAS staining) Data are expressed as mean ± SEM (𝑛≥6 per group); ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001 significantly different from control; ^#𝑃<0.05 significantly different from diabetic.