Research Article

Neopterin and Beta-2 Microglobulin Relations to Immunity and Inflammatory Status in Nonischemic Dilated Cardiomyopathy Patients

Table 1

Clinical data of all dilated cardiomyopathy patients (DCM) and comparison between groups A and B.

DCM
= 169
Group A
= 46
Group B
= 123
A versus B

Sex M/F133/3640/693/30ns
Age, y (±SD)43.2 (±10.4)44.01 (±9.9)42.9 (±10.5)ns
Hypertension (%)49 (28.99)13 (28.26)36 (29.26)ns
Diabetes mellitus (%)10 (5.91)3 (6.52)7 (5.69)ns
Prior infection (%)33 (19.52)10 (21.73)24 (18.69)ns
NYHA functional class
I/II/III/IV (%)
13/90/58/8
(8/53/34/5)
2/16/26/2
(4/35/57/4)
11/74/32/6
(9/60/26/5)
<0.05
ECG (%)
 Normal16 (9.4)5 (10.8)11 (8.9)ns
 LBBB32 (18.9)8 (17.3)24 (19.51)ns
 RBBB7 (4.14)2 (3.34)5 (4.06)ns
 Atrial fibrillation37 (21.89)11 (23.91)26 (21.13)ns
 LV-overload38 (22.48)11 (23.91)27 (21.95)ns
UKG   ± SD
 EF (%)29.67 ± 11.3728.67 ± 11.2730.04 ± 11.41ns
 LV EDV (mL)189.81 ± 79.07196.30 ± 76.77187.39 ± 80.4ns
 LVESV (mL)139.53 ± 68.72144.43 ± 63.17137.71 ± 70.8ns
 Left atrium (cm2)21.96 ± 5.4522.69 ± 5.3021.69 ± 5.51ns
 Right ventricle (cm)3.32 ± 0.593.39 ± 0.63.30 ± 0.59ns
Biopsy
 CD3 (/HPF)1.04 ± 0.751.99 ± 0.780.68 ± 0.70<0.01
 Mac (/HPF)2.25 ± 2.013.31 ± 2.991.86 ± 1.65<0.01
 Dallas active (%)20 (11.8%)12 (26.1%)8 (6.5%)<0.01
 Dallas borderline70 (41.4%)22 (47.8%)48 (39.0%)ns
 Dallas no MCI79 (46.8%)12 (26.1%)67 (54.5%)<0.01