Epigallocatechin-3-gallate Ameliorates Seawater Aspiration-Induced Acute Lung Injury via Regulating Inflammatory Cytokines and Inhibiting JAK/STAT1 Pathway in Rats
Figure 4
Effect of EGCG pretreatment on the histopathologic changes in lungs in seawater aspiration-induced ALI: (a) control group: the lung structure was normal; (b) EGCG (10 mg/kg) group: there was no obvious change in lung structure compared with control group; (c) seawater group (4 mL/kg): alveolar wall thickened, edema and hemorrhage, less alveolar space and obvious inflammatory cells infiltration into interstitial and alveolar spaced; (d) seawater (4 mL/kg) + EGCG (10 mg/kg): lung injury was significantly alleviated compared with seawater group (hematoxylin and eosin staining, original magnification 200×).
