No Signs of Inflammation during Knee Surgery with Ischemia: A Study Involving Inhaled Nitric Oxide
Figure 4
There was a significant increase in methemoglobin levels compared with baseline for the iNO treated patients and a significant difference over time in contrast to the placebo treated (); also, a significant difference between the two iNO groups was observed (#). Groups 1 (iNO) and 3 (placebo, N2) received iNO 80 ppm or placebo throughout the entire operation, whereas group 2 (piNO) only received iNO 80 ppm in the beginning and at the end of the operation. Time point 1; before the spinal anesthesia, time point 2; before tourniquet activation, and time point 3; after tourniquet release. Mean ± SEM.
