No Signs of Inflammation during Knee Surgery with Ischemia: A Study Involving Inhaled Nitric Oxide

Table 1

Patient characteristics.

	Group 1 (iNO)	Group 2 (piNO)	Group 3 (placebo)
Patients,	15	15	15
Gender (F/M)	8♀/7♂	10♀/5♂	13♀/2♂
Mean age, years	63 ± 14	65 ± 9	64 ± 9
Mean BMI	27.3 ± 4.6	29.8 ± 6.1	30.8 ± 5.4
Tourniquet time, min	101 ± 20; range 74–127	103 ± 19; range 70–140	95 ± 19; range 60–121
Total duration of surgery, min	170 ± 31; range 114–223	168 ± 20; range 125–207	156 ± 32; range 98–204
Total time of iNO, min	196 ± 36; range 131–259	97 ± 16; range 71–132	—

iNO: inhaled nitric oxide, piNO: partial iNO. Groups 1 (iNO) and 3 (placebo, N₂) received iNO 80 ppm or placebo throughout the entire operation, whereas group 2 (piNO) received iNO 80 ppm in the beginning and at the end of the operation, with a break in iNO administration during the period of activated tourniquet. Values are expressed as mean ± SD if not stated otherwise.