Impact of Cyclosporine Levels on the Development of Acute Graft versus Host Disease after Reduced Intensity Conditioning Allogeneic Stem Cell Transplantation

Table 2

Description of Csa levels during the first four weeks after stem cell transplantation.

CsA blood concentration; median (range) ng/mL
First week	134 (10–444)
Second week	219 (54–656)
Third week	253 (53–910)
Fourth week	224 (30–699)
Patients with CsA median levels in the optimal range (200–300 ng/mL); 𝑛 (%)
First week	22/149 (15%)
Second week	67/153 (44%)
Third week	66/148 (45%)
Fourth week	53/123 (43%)
Patients with one or more CsA blood level(s) below 150 ng/mL; 𝑛 (%)
First week	124 (83%)
Second week	51 (33%)
Third week	28 (19%)
Fourth week	26 (21%)
Patients with CsA median levels lower than 150 ng/mL 𝑛 (%)
First week	89 (60%)
Second week	24 (16%)
Third week	16 (11%)
Fourth week	21 (17%)

Note: CsA: cyclosporine A.