Intraperitoneal Infusion of Mesenchymal Stem/Stromal Cells Prevents Experimental Autoimmune Uveitis in Mice

Figure 2

Flow cytometry for Th1 and Th17 cells in LNs. Time course study demonstrated that the percentages of IFN-γ-expressing CD4⁺ cells or IL-17A-expressing CD4⁺ cells were significantly increased in popliteal (a) and inguinal LNs (b) on day 7 after EAU induction and decreased thereafter to baseline until day 21. The percentages of both Th1 and Th17 cells were significantly lower in EAU mice treated with hMSCs, compared to BSS-treated mice. Data are presented in mean ± SEM. 𝑛=5 in each group.

(a)

(b)