Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans
Table 1
Physical, clinical, and biochemical characteristics of the study population at baseline.
Lean ()
Obese ()
value
Physical and clinical characteristics
Gender (M/F)
6/11
22/18
0.18
Age (year)
0.06
BMI (kg/m2)
<0.0001
PBF (%)
<0.0001
Waist (cm)
<0.0001
Hip (cm)
<0.0001
Resting HR (beat/min)
0.94
SBP (mmHg)
0.09
DBP (mmHg)
0.94
(mL/kg/min)
0.22
Metabolic markers
Cholesterol (mmol/L)
0.20
HDL (mmol/L)
0.06
LDL (mmol/L)
0.62
TG (mmol/L)
0.013
Glucose (mmol/L)
0.035
HBA1c (%)
0.013
C-peptide (ng/mL)
0.29
Insulin (ng/mL)
0.12
Leptin (ng/mL)
0.0006
PAI-1 (ng/mL)
0.41
Resistin (ng/mL)
0.04
Visfatin (ng/mL)
0.86
Inflammatory markers
TNF- (pg/mL)
0.49
IL-1 (pg/mL)
0.72
IL-1ra (pg/mL)
0.38
IL-4 (pg/mL)
0.50
IL-6 (pg/mL)
0.40
IL-10 (pg/mL)
0.85
IP-10 (pg/mL)
0.0008
MCP-1 (pg/mL)
0.56
MIP-1a (pg/mL)
0.13
MIP-1b (pg/mL)
0.36
RANTES (ng/mL)
0.023
Oxidative stress markers
ROS (mM)
0.33
TBARS (M)
0.07
Data were adjusted for age and gender and presented as mean ± SE. BMI: body mass index, PBF: percent body fat, HR: heart rate, SBP: systolic blood pressure, DBP: diastolic blood pressure, : maximum oxygen consumption, HDL: high density lipoprotein, LDL: low density lipoprotein, and TG: triglycerides.