Research Article

Angiogenesis-Related Biomarkers in Patients with Alcoholic Liver Disease: Their Association with Liver Disease Complications and Outcome

Table 1

Basic characteristics of patients with ALD based on their gender .

ALD group ( )
Females ( )Males ( )
Median95% CI25–75 PMedian95% CI25–75 P

Age
years
51.0048.03–54.9645.00–56.0051.0048.00–52.4940.00–60.000.19

ALT
IU/L
39.5028.03–44.9323.00–47.0056.0050.00–69.0035.25–84.000.004

ASP
IU/L
100.5078.45–114.9066.00–120.00110.0078.51–131.0064.50–189.000.72

AP
IU/L
118.50111.68–156.27105.00–179.00129.00118.00–148.0079.00–223.000.62

GGT
IU/L
415.00174.00–543.00172.00–772.00359.00200.50–504.8893.00–1066.000.020

T-Bil
mg/dL
4.203.51–5.273.30–8.403.001.75–4.001.10–8.100.70

Alb
g/dL
3.102.70–3.292.63–3.503.203.00–3.302.73–3.610.12

INR1.451.39–1.641.31–1.711.211.16–1.301.07–1.430.034

Crea
mg/dL
0.800.70–0.800.70–1.000.900.90–1.000.80–1.100.51

Na
mEq/L
139.00136.03–140.96134.00–141.00138.00136.51–139.00134.00–140.000.38

Hgb
g/dL
11.2010.34–11.509.70–12.0012.1011.60–12.7010.30–13.50<0.001

RBC
×106 kom/uL
3.173.08–3.502.86–3.523.863.57–3.973.15–4.11<0.001

PLT
×103 kom/uL
135.50114.38–137.9697.00–251.00136.00116.00–166.4680.00–202.000.81

WBC
×103 kom/uL
8.125.42–11.634.89–13.047.126.30–8.285.01–10.800.75

NEUT
×103 kom/uL
8.443.20–8.972.57–13.515.024.19–6.102.91–7.920.053

NLR4.382.34–4.522.34–7.633.473.26–4.452.13–6.040.12

CRP
mg/L
17.3316.19–33.145.98–42.1717.5313.40–21.305.01–43.000.58

mDF17.3512.00–22.969.00–28.009.006.00–12.004.00–16.740.21

MELD17.5015.03–18.0012.00–20.0015.0014.00–16.0011.00–17.000.047

CTP9.509.00–10.008.00–10.007.007.00–8.007.00–9.00<0.001

Alb: albumin (normal range (NR) 3.2–4.8); ALT: alanine aminotransferase ((NR) < 31); AP: alkaline phosphatase (NR 45–129); AST: aspartate aminotransferase (NR < 34); Crea: creatinine (NR 0.5–1.1); CRP: C-reactive protein (NR 0.0–5.0); CTP: Child-Turcotte-Pugh score; GGT: gamma-glutamyl transpeptidase (NR < 50.0); Hgb: hemoglobin (NR 14.0–18.0); INR: international normalized ratio (NR 0.8–1.2); MELD: model for end-stage liver disease; Na: sodium (NR 136–145); NEUT: neutrophils (NR 1.8–7.7); NLR: neutrophil to lymphocyte ratio; PLT: platelets (NR 130–400); 25–75 P: percentiles; RBC: red blood cells (NR 4.5–6.1); T-Bil: total bilirubin (NR 0.3–1.2); WBC: white blood cells (NR 4.8–10.8).