Troglitazone and Δ2Troglitazone Enhance Adiponectin Expression in Monocytes/Macrophages through the AMP-Activated Protein Kinase Pathway
Figure 1
Chemical structures of troglitazone and its PPARγ-inactive analogues Δ2troglitazone (Δ2TG). The introduction of the double bond adjoining the terminal thiazolidinedione ring results in the abrogation of the PPARγ ligand property of Δ2TG.