The Macrophage Inflammatory Proteins MIP1 (CCL3) and MIP2 (CXCL2) in Implant-Associated Osteomyelitis: Linking Inflammation to Bone Degradation
Figure 2
Biopsy of a patient with infection and massive osteolysis: (a) HE staining shows degraded bone (star) and osteoclasts (arrow head) in the immediate vicinity. Moreover, neutrophils and mononuclear cells are seen (arrows). (b) Specific staining for CCL3 indicated by brownish coloring is mostly associated with mononuclear cells (arrows).