Impaired Resolution of Inflammation in the Endoglin Heterozygous Mouse Model of Chronic Colitis

Table 2

Distribution and number of major colonic leukocytes during DSS-induced colitis in Eng ^+/+ and Eng ^+/− mice.

Experimental day(s)	Percent CD45^+ cells
	B cells		T cells		Myeloid cells
	Eng ^+/+	Eng ^+/−	Eng ^+/+	Eng ^+/−	Eng ^+/+	Eng ^+/−
0	31±5	35±5	14±1	13±1	22±3	19±2
7–9	33±1	35±8	14±1	14±1	37±1^∗	32±8
18–23	33±2	26±4	16±1	16±1	23±1	30±5^#
	Total number of cells (×10^6)
	B cells		T cells		Myeloid cells
0	0.4±0.1	0.5±0.1	0.2±0.01	0.2±0.01	0.3±0.02	0.3±0.04
7–9	0.9±0.1	1.6±0.4	0.5±0.1	0.6±0.1	1.2±0.2	1.5±0.3
18–23	2.5±0.3^∗	2.3±0.4^∗	1.2±0.2^∗	1.5±0.2^∗	1.8±0.2^∗	2.9±0.8^∗

Results represent mean ± SEM (for both genotypes, 𝑁=3 experiments for day 0, 5 for days 7–9 and 4 for days 18–23, with 3-4 mice/experiment). ^∗𝑃<0.05 versus corresponding day 0, ^#𝑃=0.08 versus corresponding day 0.