Quercetin Protects against Obesity-Induced Skeletal Muscle Inflammation and Atrophy
Table 2
Body weight, food intake, and organ weight.
Groups
RD
HFD
HFD/Q0.05
HFD/Q0.1
Initial weight (g)
20.99 ± 0.40
20.91 ± 0.37
20.71 ± 0.33
20.79 ± 0.33
Final weight (g)
27.63 ± 0.49
41.78 ± 1.56**
37.75 ± 1.48
39.33 ± 1.66
Food intake (g/day)
4.15 ± 0.05
3.15 ± 0.08*
3.13 ± 0.08
3.27 ± 0.08
Energy intake (Kcal/d)
13.28 ± 0.15
16.48 ± 0.41*
16.37 ± 0.42
17.19 ± 0.45
Epididymal fat (g)
0.22 ± 0.05
2.62 ± 0.15**
2.02 ± 0.29
2.26 ± 0.13
Total muscle weight (mg)
655.42 ± 7.76
608.26 ± 9.17**
648.55 ± 10.25
648.82 ± 14.62
Quadriceps (mg)
353.53 ± 6.46
317.58 ± 8.10**
344.35 ± 6.80
342.91 ± 10.67
Gastrocnemius (mg)
284.05 ± 3.04
274.42 ± 3.78
286.88 ± 4.78
288.48 ± 4.55
Soleus (mg)
14.84 ± 0.54
16.26 ± 0.47
17.31 ± 0.83
17.43 ± 0.59
Eight-week-old male C57BL/6 mice were fed a regular diet (RD), a high-fat diet (HFD), or an HFD supplemented with 0.05% quercetin (HFD/Q0.05) or 0.1% quercetin (HFD/Q0.1) for 9 weeks. Data are means ± SEM of 6 animals per group. and between the HFD and RD groups; between the HFD/Q0.05, HFD/Q0.1 groups and the HFD group.
