Maternal Plasma and Amniotic Fluid Chemokines Screening in Fetal Down Syndrome

Table 5

Diagnostic values of chemokines in amniotic fluid.

	Threshold value (pg/mL)	Sensitivity	95% CI for sensitivity	Specificity	95% CI for specificity	AUC	95% CI for AUC	Std. error	value
IP-10	>1152.5	0.8571	0.4868–0.9743	0.7857	0.5241–0.9242	0.8673	0.729–1	0.08	<0.0001
MPIF-1	>189.62	1	0.6456–1	0.5	0.2679–0.7320	0.7857	0.6075–1	0.1	0.0041
CXCL7	>479.81	0.8571	0.4868–0.9743	0.7857	0.5241–0.9242	0.8469	0.7034–1	0.08	<0.0001
6Ckine	<5415.84	0.8571	0.4868–0.9743	0.7857	0.5241–0.9242	0.7857	0.5666–1	0.13	0.0159
I-TAC	<34.21	0.8333	0.4364–0.9699	0.9166	0.6461–0.9851	0.875	0.7198–1	0.09	<0.0001
MCP-3	<24.49	1	0.5101–1	0.833	0.5519–0.9530	0.875	0.7222–1	0.09	<0.0001
MIF	<1483.82	0.8571	0.4868–0.9743	0.9166	0.6461–0.9851	0.8809	0.7385–1	0.08	<0.0001