Uteroglobin, a Possible Ligand of the Lipoxin Receptor Inhibits Serum Amyloid A-Driven Inflammation

Figure 2

SAA-induced phospholipase A₂ activity is attenuated by UG in CHO cells overexpressing ALX. Time response of SAA-induced PLA₂ activity in CHO^ALX cells (a) over a 5-minute monitoring period in the presence and absence of UG, as compared to mock transfected CHO cells (b). Significance is noted by Student’s 𝑡-test of SAA treatment versus SAA + UG treatment. * for 𝑃<0.005 and ** for 𝑃<0.001. Results represent the mean ± SD of four separate experiments with triplicate determinations.

(a)

(b)