The Effect of Serine Protease Inhibitors on Airway Inflammation in a Chronic Allergen-Induced Asthma Mouse Model
Effects of protease inhibitors on Der p-induced airway inflammation, goblet cell hyperplasia, mucus hypersecretion, and collagen deposition in mouse lung tissues. (a) Goblet cells (PAS; original magnification, ×400) in airway epithelial cells and (b) goblet cell hyperplasia was scored on a 5-point scale (0–4). (c) Collagen contents in lung tissue results are expressed as means ± SD’s for 6 mice/group. versus naïve group; between Der p-treated groups.