Intestinal Mucosal Barrier Is Injured by BMP2/4 via Activation of NF-B Signals after Ischemic Reperfusion
Figure 1
The expression of BMP2 and BMP4 in intestinal epithelial cells. (a) and (b) The IEC-6 cells were treated with hypoxia (1% O2) for 6 h. Hypoxia caused a dramatic increase in BMP2 and BMP4 protein expression as detected by Western blotting. versus control. Data are representative of 3 similar experiments. (c) The level of BMP2 protein expression significantly increased in the mid-to-distal villus region after 1 h of I/R, while the level of BMP4 protein expression also significantly increased in both the villi and mesenchyme.
