Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing

Table 1

Baseline characteristics and serum lipid levels of subjects and patients in the two groups.

	Control group (𝑛=11)	Research group (𝑛=39)	𝑃
Age, yrs	57±5	60±6	0.144
Male sex, 𝑛 (%)	7 (64%)	27 (69%)	0.745
Smoker, 𝑛 (%)	0	8 (20%)
Hypertension, 𝑛 (%)	0	17 (44%)
Diabetes, 𝑛 (%)	0	15 (38%)
TG (mmol/L)	1.31±0.46	1.95±1.16	0.078
TC (mmol/L)	3.55±0.26	4.99±1.47	<0.01
LDL-C (mmol/L)	2.05±0.21	3.15±1.24	<0.01
HDL-C (mmol/L)	1.78±0.25	1.26±0.36	<0.01
Lp (a) (mg/dL)	19.87±7.31	30.45±23.53	0.025
ApoA (g/L)	1.42±0.18	1.08±0.25	<0.01
ApoB (g/L)	0.85±0.13	0.91±0.28	0.245