Myocardial Gene Expression of T-bet, GATA-3, Ror-t, FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed TH1-Type Response
Figure 1
Expression of mRNA encoding transcription factors T-bet, Gata-3, and Rorγ-T in myocardium. Real-time qPCR analysis of mRNA expression in CCC and NIC myocardium. After normalization to GAPDH mRNA, relative increase was plotted in comparison to N group and data were calculated with the method, as described in Methods section. The horizontal bar stands for the median; dotted lines indicate twofold increase or decrease of expression as compared with the control group.
