Glucagon-Like Peptide-1 Secreting Cell Function as well as Production of Inflammatory Reactive Oxygen Species Is Differently Regulated by Glycated Serum and High Levels of Glucose
Figure 2
GS and HG increase proglucagon mRNA expression. Semiquantitative RT-PCR of proglucagon mRNA expression in GLUTag cells stimulated standard medium (CTR) or high glucose concentration (25 mmol/L) (HG) in presence of different concentrations of glycated serum (400 [GS] and 800 nmol/L [2GS]). (a) Representative agarose gel. (b) Quantification of densitometries of agarose gel bands. Data are represented as mean ± SE (). versus CTR.