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Mediators of Inflammation
Volume 2014, Article ID 926875, 10 pages
Research Article

IL-27 Activates Human Trophoblasts to Express IP-10 and IL-6: Implications in the Immunopathophysiology of Preeclampsia

1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China
2Laboratory of Lipid & Glucose Research, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China

Received 29 October 2013; Accepted 25 December 2013; Published 10 February 2014

Academic Editor: Eric F. Morand

Copyright © 2014 Nanlin Yin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The optimal concentrations of different specific signaling molecule inhibitors on HTR-8/SVneo were determined by MTT assay. (a)JAK inhibitor AG490 (b)NF-?B inhibitor BAY1167082 (c)PI3K inhibitor LY294002 (d) p38 MAPK inhibitor SB203580 (e) JNK inhibitor SP600125 (f)ERK inhibitor U0126. All the experiments were performed in three independent replicates.

  1. Supplementary Material