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Mediators of Inflammation
Volume 2014, Article ID 938712, 11 pages
Research Article

Leukocyte Production of Inflammatory Mediators Is Inhibited by the Antioxidants Phloretin, Silymarin, Hesperetin, and Resveratrol

Department of Periodontics (MC 859), College of Dentistry, University of Illinois at Chicago, 801 South Paulina Street, 458 DENT, Chicago, IL 60612-7212, USA

Received 27 August 2013; Revised 9 January 2014; Accepted 11 January 2014; Published 24 February 2014

Academic Editor: Vera L. Petricevich

Copyright © 2014 Jezrom B. Fordham et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Peripheral Blood Mononuclear Cells (PBMC) from 3 biological donors were activated with lipopolysaccharide from Aggregatibacter actinomycetemcomitans (Y4) and the supernatant was assayed for TNF-α, IL-1α, IL-1β, G-CSF, GM-CSF, IFN-γ, IL-6, IL-10, MCP-1, CCL5, MIP-1α, MIP-1β, IL-Ra, CXCL5, CXCL8 (IL-8), VEGF, IL-4, FGF basic, IL-2, IL-5, IL-17, and TPO after 18 hrs via cytometric bead array.

  1. Supplementary Material