Clinical Study

Enhanced Apoptosis of Monocytes from Complication-Free Juvenile-Onset Diabetes Mellitus Type 1 May Be Ameliorated by TNF-α Inhibitors

Table 2

Apoptotic cells within the monocyte subsets.

CD14++CD16 classicalCD14+CD16+ nonclassical
HealthyDM1HealthyDM1

% of apoptotic cells within subset22.0 ± 7.151.6 ± 21.118.5 ± 10.145.5 ± 18.2
Statistical significance P 0.00000.0000
Absolute number of apoptotic cells/mm3193.8 ± 12.1314.7 ± 37.45.01 ± 0.4524.6 ± 3.8
Statistical significance P 0.00000.0000

Values are presented as arithmetic means ± S.D.; DM1—diabetes mellitus type 1.
Statistical differences were calculated between the values for the patients and those for healthy controls within each monocyte subset.