Research Article

Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation

Table 1

Clinical characteristics of patients with and without MACEs.

All patients ( = 596)Patients without MACEs ( = 514)Patients with MACEs ( = 82) value

Age (years) 65.9 (8.1)65.3 ± 8.169.7 ± 7.30.000
Male, (%)467 (78.4)402 (78.2)65 (79.3)0.886
CCSA class > II, (%)184 (30.9)149 (29.0)35 (42.7)0.015
LVEF < 50%, (%)178 (29.8)145 (28.2)33 (40.2)0.037
Diabetes mellitus, (%)92 (15.4)73 (14.6)19 (20.7)0.047
Hypertension, (%)319 (53.5)272 (52.9)47 (57.3)0.477
Hyperlipidemia, (%)192 (32.2)164 (31.9)28 (34.1)0.704
Current smoking, (%)182 (30.5)153 (29.8)29 (35.4)0.368
cTnI (ng/mL)0.23 ± 0.160.20 ± 0.120.37 ± 0.240.000
HsCRP (ng/mL)3.27 ± 1.193.14 ± 1.144.09 ± 1.160.000
In-hospital therapy
 Aspirin, (%)596 (100)514 (100)82 (100)
 Clopidogrel, (%)596 (100)514 (100)82 (100)
-Blockers, (%)465 (78.0)404 (78.6)61 (74.4)0.391
 ACE-I or ARB, (%)532 (89.3)463 (90.1)69 (84.1)0.123
 Statins, (%)596 (100)514 (100)82 (100)
Types of DES
 Sirolimus, (%)390 (65.4)334 (65.0)56 (68.3)0.618
 Zotarolimus, (%)130 (21.8)113 (22.0)17 (20.7)0.886
 Paclitaxel, (%)63 (10.6)53 (10.3)10 (12.2)0.565
 Others, (%)13 (2.2)10 (1.9)3 (3.7)0.403
Multiple stents, (%)238 (39.9)190 (37.0)48 (58.5)0.0004

CCSA: Canadian Cardiovascular Society Angina; LVEF: left ventricular ejection fraction; PTX3: pentraxin-3; cTnI: cardiac troponin I; HsCRP: high-sensitivity C-reactive protein; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin-receptor blocker.