Alleviation of Antioxidant Defense System by Ozonized Olive Oil in DNBS-Induced Colitis in Rats
Figure 2
Histopathological findings of colonic tissues from different animals’ groups; (a) colonic tissue for animals treated with OO shows normal surface epithelium and crypt cells ×400. (b) Colonic tissue for animals treated with high dose OZO alone with normal surface epithelium and crypt cells ×200. (c) Inflamed control group; the mucosa shows focal loss of the covering and lamina propria shows dense lymphoplasmacytic and histiocytic infiltrate to the submucosa ×200. (d) Inflamed animals treated with OO; mononuclear granulomatous infiltrate encroaching on the overlying mucosa with apparent destruction of the muscularis mucosa and mucosal covering ×200. (e) Inflamed animals treated with low dose OZO nearly normal mucosa and submucosa with polypoid formation. Crypt cell hyperplasia and elongation. Lamina propria is infiltrated by monocytes and eosinophils 400x. (f) Inflamed animals treated with high dose OZO, showing normal mucosal lining and submucosa and cellular infiltrate with eosinophils 200x.
