Involvement of Proteasome and Macrophages M2 in the Protection Afforded by Telmisartan against the Acute Myocardial Infarction in Zucker Diabetic Fatty Rats with Metabolic Syndrome

Table 1

Effects of telmisartan treatment on acute myocardial I/R injury in ZDF rats.

Drug treatment	IS (%AR)	AR (%LV)	IS (%LV)
Vehicle	68±5.4	61±1.8	36±1.1
Tel 7 mg/kg	48±4.7^∗	58±1.5	28±2.9^∗
Tel 12 mg/kg	30±3.4^∗∗	59±1.3	20±1.8^∗∗

Tel = telmisartan; I/R = ischemia/reperfusion; IS = infarct size; AR = area at risk; LV = left ventricle. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 versus vehicle.