iNOS Activity Modulates Inflammation, Angiogenesis, and Tissue Fibrosis in Polyether-Polyurethane Synthetic Implants

Figure 3

Modulation of cytokines, but not chemokines production, in implants from iNOS^−/− mice. TNF-α (a), IL-10 (b), CXCL1/KC (c), CCL2/MCP-1 (d), and IFN-γ (e) levels were evaluated by sandwich-type ELISA. The sponges were collected at day 14 after implantation. Values were represented as means (±SEM) from groups of 8 animals each. , , and versus WT group (Student’s -test).

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