Mediators of Inflammation / 2015 / Article / Tab 2

Research Article

Polymorphisms of Tumor Necrosis Factor Alpha in Moroccan Patients with Gastric Pathology: New Single-Nucleotide Polymorphisms in TNF-α−193 (G/A)

Table 2

Association of a new single-nucleotide polymorphisms TNF-−193 (G/A) with gastric pathology.

GenotypesGenotyping frequencyMAFORIC value

Healthy patientsG/G56 (75.68)0.02
A/G + A/A16 (21.62)

AdenocarcinomaG/G77 (82.8)0.120.64 (0.30–1.38)0.25NS
A/G + A/A16 (17.2)

GastritisG/G44 (78.6)0.180.84 (0.36–1.94)0.69NS
A/G + A/A12 (21.4)

UlcerG/G11 (52.38)0.402.821.03–7.740.03S
A/G + A/A10 (47.62)

Data are expressed as %. TNF-: tumor necrosis factor alpha; A/G: adenine/guanidine; MAF: minor allele frequency; S: significant; NS: not significant ORs with 95% CI; and values were calculated for wild/wild genotype versus wild/mutant and mutant/mutant genotypes.