Mediators of Inflammation / 2015 / Article / Fig 2

Research Article

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

Figure 2

Intravitreal Resolvin D1 (RvD1) reduces CD4+ immunostaining. (a) Representative immunohistochemistry of ocular tissues showing that treatment with RvD1 decreases immunostaining for CD4+ T cells, already significant at the lowest dose (10 ng/kg, 1 h post-LPS treatment) with respect to the LPS treated rats. (b) Graph showing the percentage of the total positive stained area for CD4+ per total area analyzed at 400x magnification. Values are mean ± SEM of observation for each group. and versus LPS-treated group. R = retina; S = sclera; Ch = Choroid; Cb = ciliary bodies.

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