Mediators of Inflammation / 2015 / Article / Fig 9

Research Article

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

Figure 9

Resolvin D1 (RvD1) treatment induces M2 expression macrophage phenotypes. (a) Representative immunohistochemistry of eye tissues showing that treatment with resolvin D1 (RvD1, 10 ng/kg 1 h post-LPS) increased immunostaining for M2 macrophage phenotype expression an anti-mannose receptor antibody CD206. (b) Graph showing the percentage of positive stained area per total area analyzed at 400x magnification. Values are mean ± SEM of observations for group. and versus LPS-treated group. R = retina; S = sclera Cb = ciliary bodies; Ch = choroid.

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