Research Article

Lack of Association between Polymorphisms of the TLR4 Gene and Infection with the Hepatitis B and C Viruses

Table 3

Association of polymorphisms of the TLR4 gene with inflammatory activity, degree of fibrosis, and liver cirrhosis in chronic HBV and HCV carriers.

InfectionInflammatory activityDegree of fibrosisCirrhosis
0-1 (%)2-3 (%)0–2 (%)3-4 (%)Yes (%)No (%)

HBV
rs4986790
 AA19 (82.6)4 (17.4)1.00020 (87)03 (13)1.0009 (18.8)39 (81.2)1.000
 AG/GG01 (100)001 (100)0001 (100)
rs4986791
 CC17 (85)03 (15)0.19117 (85)03 (15)1.0007 (17.5)33 (82.5)1.000
 CT/TT0 01 (100)01 (100)0001 (100)

HCV
rs4986790
 AA34 (64.1)19 (35.9)0.14638 (70.4)16 (29.6)0.63417 (25.4)50 (74.6)0.331
 AG/GG01 (20)04 (80)03 (60)02 (40)005 (100)
rs4986791
 CC34 (63)20 (37)0.29036 (69.2)16 (30.8)0.58717 (25)51 (75)0.567
 CT/TT01 (25)03 (75)02 (50)02 (50)004 (100)