Research Article
Lack of Association between Polymorphisms of the TLR4 Gene and Infection with the Hepatitis B and C Viruses
Table 3
Association of polymorphisms of the TLR4 gene with inflammatory activity, degree of fibrosis, and liver cirrhosis in chronic HBV and HCV carriers.
| Infection | Inflammatory activity | | Degree of fibrosis | | Cirrhosis | | 0-1 (%) | 2-3 (%) | 0–2 (%) | 3-4 (%) | Yes (%) | No (%) |
| HBV | rs4986790 | | | | | | | | | | AA | 19 (82.6) | 4 (17.4) | 1.000 | 20 (87) | 03 (13) | 1.000 | 9 (18.8) | 39 (81.2) | 1.000 | AG/GG | 01 (100) | 0 | 01 (100) | 0 | 0 | 01 (100) | rs4986791 | | | | | | | | | | CC | 17 (85) | 03 (15) | 0.191 | 17 (85) | 03 (15) | 1.000 | 7 (17.5) | 33 (82.5) | 1.000 | CT/TT | 0 | 01 (100) | 01 (100) | 0 | 0 | 01 (100) |
| HCV | rs4986790 | | | | | | | | | | AA | 34 (64.1) | 19 (35.9) | 0.146 | 38 (70.4) | 16 (29.6) | 0.634 | 17 (25.4) | 50 (74.6) | 0.331 | AG/GG | 01 (20) | 04 (80) | 03 (60) | 02 (40) | 0 | 05 (100) | rs4986791 | | | | | | | | | | CC | 34 (63) | 20 (37) | 0.290 | 36 (69.2) | 16 (30.8) | 0.587 | 17 (25) | 51 (75) | 0.567 | CT/TT | 01 (25) | 03 (75) | 02 (50) | 02 (50) | 0 | 04 (100) |
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