Anti-Inflammatory Effects of a Methanol Extract from the Marine Sponge Geodia cydonium on the Human Breast Cancer MCF-7 Cell Line

Figure 2

Statistically significant cytokine levels (expressed in pg/mL) evaluated in MCF-7 cells before and after treatment with different concentrations of sponge extract. Asterisks indicate the statistically significant differences between levels of untreated (used as controls and indicated with CTRL) and treated cells with using the -test. In the legend, we report the meaning of the bars by using different colors for untreated cells (CTRL) and three different treatments. In detail, we report CXCL8 (C-X-C motif ligand 8), CCL2 (C-C motif ligand 2), VEGF (vascular endothelial growth factor), IFNG (interferon gamma), CXCL10 (C-X-C motif ligand 10), and TNF-α (tumor necrosis factor alpha).