Mediators of Inflammation / 2015 / Article / Fig 3

Research Article

Expression and Function of Hypoxia Inducible Factor-1α and Vascular Endothelial Growth Factor in Pulp Tissue of Teeth under Orthodontic Movement

Figure 3

Immunohistochemistry analysis of VEGF protein expression in rat dental pulp tissue after orthodontic force. VEGF protein was weakly stained in control group (a). VEGF protein became slightly stained after 1 d of orthodontic force (b). (c–e) VEGF protein expression became positively stained after 3 d, 7 d, and 2 w after orthodontic force and also reached the peak level at 2 w group. VEGF protein expression then declined in the 4 w group (f). Arrows indicate the vessel wall (images on the left: magnification ×200, bar = 100 μm; images on the right: magnification ×1000).

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