Review Article

Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation

Table 1

Major agents that cause pulmonary injury.

Cell typeAgents

Alveolar types I and II cellsPulmonary aspiration (HCl), trauma, lung infection (alive microbes or microbes secreted molecules), smoke inhalation (tobacco and other molecules), oleic acid, LPS, drug overdose, and inflammatory mediators

Endothelial cellsSystemic infection (sepsis, alive microbes or metabolic products), oleic acid, LPS, fatty embolism, large volume blood replacement, burn injury, inflammatory mediators, and autoantibodies