Research Article

Clinical Features and Genetic Background of the Periodic Fever Syndrome with Aphthous Stomatitis, Pharyngitis, and Adenitis: A Single Center Longitudinal Study of 81 Patients

Table 4

Laboratory parameters of PFAPA patients.

Laboratory parameterMean ± SD (range)

IgA 1.20 ± 0.60 g/L (0.29–3.03 g/L)
IgG 10.18 ± 2.41 g/L (2.4–17.7 g/L)
IgM0.97 ± 0.35 g/L (0.35–1.76 g/L)

Laboratory parameter (%)

IgD<100 IE/mL39/48 (81%)
>100 IE/mL9/48 (19%)
Antinuclear antigen antibodiesNegative41/41 (100%)
Lymphocyte subsetsNormal28/40 (70%)
Elevated10/40 (25%)
Low 2/40 (5%)
Antistreptolysin O titerASO < 52 units/mL44/64 (69%)
52 < ASO < 500 units/mL12/64 (19%)
500 < ASO < 1000 units/mL6/64 (9%)
ASO > 1000 units/mL2/64 (3%)